Automated design of paralogue ratio test assays for the accurate and rapid typing of copy number variation
نویسندگان
چکیده
منابع مشابه
Automated design of paralogue ratio test assays for the accurate and rapid typing of copy number variation
MOTIVATION Genomic copy number variation (CNV) can influence susceptibility to common diseases. High-throughput measurement of gene copy number on large numbers of samples is a challenging, yet critical, stage in confirming observations from sequencing or array Comparative Genome Hybridization (CGH). The paralogue ratio test (PRT) is a simple, cost-effective method of accurately determining cop...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2013
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btt330